Changes in Insulin Resistance and HbA1c Are Related to Exercise-Mediated Changes in Body Composition in Older AdultsWith Type 2 Diabetes Interim outcomes from the GREAT2DO Trial
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چکیده
RESEARCHDESIGNANDMETHODSdOne-hundred three participants were randomized to receive either PRT or sham exercise 3 days per week for 12months. Homeostatic model of assessment 2 (HOMA2-IR) and glycosylated hemoglobin (HbA1c) were used as indices of IR and glucose homeostasis. Skeletal muscle mass (SkMM) and total fat mass were assessed using bioelectrical impedance. Visceral adipose tissue, mid-thigh cross-sectional area, and mid-thigh muscle attenuation were quantified using computed tomography.
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